Eli5: Why does weed make many adults feel paranoid, overwhelmed, etc. while it acts like an escape or stress relief for others?

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Why is it so polarizing?

Even people who used to smoke a lot just can t anymore, myself included: I used to exclusively smoke until my early 20s; Now even a couple tokes make me either feel self conscious or totally overwhelmed and „braindead“.

Others have the exact opposite effect, where it makes them super relaxed or even forget all their worries to a point that they need to stop to confront their problems.

In: Biology