eli5 why organs like liver, kidney, heart, lung require rejection meds, but blood transfusions apparently don’t.

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eli5 why organs like liver, kidney, heart, lung require rejection meds, but blood transfusions apparently don’t.

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* Putting some stuff in your bloodstream doesn’t trigger your immune system as much as putting a whole organ in your body.

* There are waaaaay more potential antigens for your body to freak out about in a liver than in some blood prepped for transfusion

* Blood cells don’t last very long, while an organ (hopefully) does.

Blood transfusion rejections can happen. They’re just pretty rare while rejections are basically certain for an organ for the reasons above.

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