eli5 Why small pox inoculation is any different from catching it naturally?

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So I’m having trouble with this, and I’ve went through different links on Google and can’t find an answer. So they would poke into sores of people who had smallpox and then proceed to cut the patient and insert the infection directly into them. I’m not understanding why catching small pox that way would be any different than catching it naturally?

I am specifically referring to how it was done during the revolutionary war, not today’s vaccines. But wouldn’t mind knowing how those two things differ as a bonus

In: Biology

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Anonymous 0 Comments

The virus in the vaccine is not, never has been, the smallpox virus. It is derived from the Cowpox virus which never was the devastating disease that smallpox was.

Read up on [Edward Jenner](https://en.wikipedia.org/wiki/Edward_Jenner)

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