Fat-soluble vitamins (DAEK) and other things stored in fat, what happens when you lose a lot of weight quickly?

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Curious to know, as we’ve all been cautioned against too much vitamin A, because it builds up in our fat stores and can become toxic to the body at high amounts. Wondering what would happen to those vitamins and the body, if anything, if someone were to lose weight quickly? And if there are other things stored in fat to be aware of.

In: Biology

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Anonymous 0 Comments

With vitamin D specifically, losing weight very quickly can “free up” vitamin D that was previously stored in fat. Apparently this can cause vitamin D toxicity [in some cases](https://www.sciencedirect.com/science/article/abs/pii/S1530891X23001490), but not frequently, and [it’s unclear](https://pubmed.ncbi.nlm.nih.gov/33792853/ ) to what extent this happens, how it’s affected by other factors like sunlight exposure, etc. 

As for other things stored in fat: weed metabolites. I’ve seen studies that say it can take months to be fully purged from the body (normally it’s a few weeks, but outliers exist). 

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