Proper exercise is hard to come by, when your back is basically broken. I want to pop some Notbuprofen and feel the burn as the pounds melt away.
In theory, a drug that stimulates the hormones that demand the burning of fat *should* be possible. Why isn’t it, and/or why has no one made this yet?
In: Biology
That’s sorta how GPL1 drugs work – on two hormones, insulin, and glucagon (as well as slowing gastric emptying).
Everyone knows insulin lowers blood sugar, but not necessarily what it does with all that sugar.
Once your cells’ energy demands are met & glycogen is full, it (over simplification) turns into fat as reserve supplies of energy when needed. When fat gets used for energy, it basically gets broken down into ketones, and some goes into gluconeogenesis.
Keto diets (under 20 carbs 75% fat) are designed to trigger ketosis.
Exercise (cardio) can trigger fat burning AFTER it’s used so much glucose insulin falls low enough that ketosis is triggered. BUT, the more you repeat that exercise, the body will adapt by increasing your emerging sugar stores (glycogen ‐ the reaon endurance athletes carbo load beforehand), so it will take longer to reach that trigger.
Burning fat, while sparing muscle mass, is the holy grail of fitness/weight loss because it’s such a complicated process, and we still don’t understand enough of it.
The brain gets a vote via appetite, hunger, and reward too. Lipolysis alone isn’t enough to solve the problem.
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