Hormone triggers are responsible for burning fat, right? Why aren’t there drugs that exploit and supercharge this process?

Question

Proper exercise is hard to come by, when your back is basically broken. I want to pop some Notbuprofen and feel the burn as the pounds melt away.

In theory, a drug that stimulates the hormones that demand the burning of fat *should* be possible. Why isn’t it, and/or why has no one made this yet?

In: Biology

Answer 1

Because all the drugs which were meant to drive fat loss by supercharging or tricking your metabolism failed to deliver enough of an effect to help an actual obese person cut tens of pounds (rather than helping a bodybuilder cut 2 extra pounds at the end of a fat loss phase before a competition) while being reasonably safe.

There is a reason why the only class of safe and effective weight loss drugs like Ozempic work primarily by making you eat less by manipulating your sensation of hunger and satiety. You have to fuck with how the body works way too much to make *calories in vs calories out* no longer work.