Proper exercise is hard to come by, when your back is basically broken. I want to pop some Notbuprofen and feel the burn as the pounds melt away.
In theory, a drug that stimulates the hormones that demand the burning of fat *should* be possible. Why isn’t it, and/or why has no one made this yet?
In: Biology
>Proper exercise is hard to come by, when your back is basically broken.
You could also just eat less calories.
Clenbuterol : ramps up your metabolism and basically makes your body run hotter than normal so your actually burning fat while sitting on the couch sweating. Add in a caffeine and some pseudoephedrine top and it works. This was a few decades ago so who knows what side effects they may have found from doing that. However it did work.
The problem is that there is no hormone that JUST controls weight loss, they do a LOT of other things in conjunction. If you just increase the hormones related to lean muscle mass that burn fat, but your body doesn’t ACTUALLY have that lean muscle mass, you could easily box your organs or give yourself a heart attack.
That said, there is just a thing as hormone therapy, but that wouldn’t be available for most people under most circumstance, as the benefit would not outweigh the risk.
Fat loss is dictated and only caused by a negative energy balance. If the net negative energy balance exists then adipose tissue is oxidised for energy. What gave you the idea that hormones cause fat burning????
Hormones are also responsible for alot of other things with the body you don’t want to fuck around with
Those drugs do exist, in fact, they have existed for quite some time already, with most of them beign adopted throught the 20th century medical practices – and usually for weight loss, appetite suppression, fatigue reduction, “anti-sleep”, cognition improvement and many other uses. Those medications are generally called stimulants.
However, most of them have been outright banned in many countries, had clinical trials suspended or have been modified and mixed with other compounds to lessen their side effects.
The main reason for this, is that most stimulants were causing higher rates of heart diseases, psychiatric conditions and death – which in term raised the costs of healthcare worldwide in short and long term. Depending on the substance, this can occur even in regular use under medical observation.
Nowadays (apart from illegal/recreational use), some of those substances did receive some “upgrades” in their composition after it was discovered as a form of treatment for certain diseases, like narcolepsy, ADHD, still for weight loss in some medical protocols.
TLDR: those drugs do exist, however they cause heart problems and death. And due to the whole thing about weight loss beign recommended is because obesity = more deaths and heart diseases, it has been determined by scientists (and countries) that for a medication like that to be legally prescribed, it needs to not cause the diseases it’s supossed to prevent.
In a more general sense, hormones do a lot more than just one thing. I learned in college “a hormone is involved in everything and responsible for nothing.” For example, you might think of serotonin as the “happy hormone,” but its also involved in digestion! I went through SSRI withdrawal once and one symptom was diarrhea. So you can’t just have more or less of one hormone to solve one specific specific problem with no side effects.
That’s sorta how GPL1 drugs work – on two hormones, insulin, and glucagon (as well as slowing gastric emptying).
Everyone knows insulin lowers blood sugar, but not necessarily what it does with all that sugar.
Once your cells’ energy demands are met & glycogen is full, it (over simplification) turns into fat as reserve supplies of energy when needed. When fat gets used for energy, it basically gets broken down into ketones, and some goes into gluconeogenesis.
Keto diets (under 20 carbs 75% fat) are designed to trigger ketosis.
Exercise (cardio) can trigger fat burning AFTER it’s used so much glucose insulin falls low enough that ketosis is triggered. BUT, the more you repeat that exercise, the body will adapt by increasing your emerging sugar stores (glycogen ‐ the reaon endurance athletes carbo load beforehand), so it will take longer to reach that trigger.
Burning fat, while sparing muscle mass, is the holy grail of fitness/weight loss because it’s such a complicated process, and we still don’t understand enough of it.
The brain gets a vote via appetite, hunger, and reward too. Lipolysis alone isn’t enough to solve the problem.
Anytime you take a drug, you’re upsetting your bodies natural rhythm and method for regulating itself. Unless you have a true medical needs, you’re better off exercising
The goo you rub on your belly to deflate fat cells and return them to the bloodstream and out the bladder, clogged up arteries quite well.
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