certain cells have certain ‘receptors’ those receptors either cause a reaction or communicate something to the cell(make more cells, release fluid, absorb sugars)
while biological chemistry only recently got to a point where they could actually design drugs, most of the time is an observed effect of some odd chemical that is then refined into a usable drug.
typically it’s on accident, then used for what it can be used for.
yes basically they have to test combinations as drug interactions can be extremely dangerous.
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