How can drugs like Ingrezza be allowed to be prescribed if the way they work isn’t understood? Shouldn’t we understand how a drug works before the FDA clears it for use?

Question

How can drugs like Ingrezza be allowed to be prescribed if the way they work isn’t understood? Shouldn’t we understand how a drug works before the FDA clears it for use?

In: Other

Answer 1

FDA authorization isn’t about making sure of *how* it works, it’s about making sure that it *does* work. “Does what they say” and “is generally safe at *this* dose” are what they’re concerned about.