Adverse side effects, like death and being really sick and in bad health is a major issue. We don’t see this much in modern times in developed countries, but in human history (and even in poor areas now) malnutrition is a major issue. Living off a single food source, or food sources poor in necessary vitamins or such can cause massive issues and death, we’re built to get a lot of stuff in our diet and need it to survive. If you’re not able to get a proper diet, things aren’t gonna go well over time.
You could live off a single source, if that contained everything you need. There are many “meal replacement” products on the market that you can live off fine, and people do (its basically a drink packed with vitamins).
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