How come drugs like tamoxifen works at high doses because it shuts down tumor growth, but at lower doses it can turn up tumor growth?

Question

How come drugs like tamoxifen works at high doses because it shuts down tumor growth, but at lower doses it can turn up tumor growth?

In: Biology

Answer 1

Can you provide a source? I haven’t been able to find anything that says tamoxifen increases tumor burden at lower doses.