Antibiotic generally refers to drugs that target and kill certain microbes. This can be things like bacteria (most commonly), or parasites or even fungi. Every antibiotic targets a specific thing. Some antibiotics target production of bacteria cell wall for example. Some target bacterial cellular machinery.
It’s not a question of size. It’s a question of finding a drug that will be specific to its target.
If you develop a drug to kill bacteria but it also targets the same human cellar structures it can cause us a lot of harm. That’s why we find ones specialized to structure unique of bacteria
Bringing this back to parasites it’s not about the size. Its about developing drugs that will kill parasites by targeting structure that are in them and aren’t in humans
TLDR; antibiotics target specific structures to kill organisms, their antibiotic properties are not caused by an organism’s size
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