if they have any sort of condition that would lead to that, they will not be in that mission period.
Astronauts get a very externsive Health screening prior to a mission with stuff as seemngly innoucous as a sniffle being a disqualifying factor.
for long temr missions where they might cvatch somethnig while up there, their diets are controlled and they monitor thesmevles in near rea ltime ot mitigate stomach and intestinal issues..if this is really not avoidable their toilers are effectively “sealed” so no danger of contamination.
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