They dont. Like Albert Hofmann who found out how to make acid or LSD. He thought well surely 250 microgram wont have any effect on humans. So he ate 250 micrograms and low and behold 250 microgram is enough for a really good intoxication.
Question is LSD toxic?
According to this definition it is
>”What makes a chemical toxic? The toxicity of a substance is its ability to cause harmful effects. These effects can strike a single cell, a group of cells, an organ system, or the entire body. A toxic effect may be visible damage, or a decrease in performance or function measurable only by a test”
https://www.purdue.edu/research/docs/pdf/Introduction%20to%20Chemical%20Hazards%20in%20the%20Workplace.pdf
And yes LSD will make you perform suboptimally on tests.
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