They’re like Lego blocks. Each individual Lego piece is a monomer of a Lego creation, and individually they do nothing. But arrange a bunch of Lego blocks in the right way and you have…just about anything.
Macromolecule monomers are the same. Nucleotides, the monomers of nucleic acids, have a “top” and “bottom” side much the same way that Lego blocks do. These sides can react with each other the way you press two Lego blocks together, to form a larger molecule made up of two nucleotides. Repeat billions of times and you build a genome, which can be read by proteins (also made up of monomers) to make proteins to make you.
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