how do NSAIDs and Tylenol work in the body?


Inspired by the same question about antibiotics a few days ago. I get that (in the case of NSAIDs) they are reducing inflammation but how? And how do they target my head or back or knee?

In: 12

Both work to reduce pain by helping block production of the bodies reaction to signal pain receptors. That includes helping temperature regulation with fevers. Ibuprofen helps with swelling amd inflammation (NSAID being non-steroidal anti-inflammatory drugs). It’s all related to calming your nervous system or signals to your brain/body. Tylenol (or acetaminophen/paracetamol) is taxing on the liver so high dosage and long-term use isn’t recommended. There are studies that suggest a combination of NSAIDs and Acetaminophen is a more efficient solution for long or chronic pain.

As to the targeting a part of your body question, they don’t. It has the same impact on your whole body (lowering inflammation, lowering pain signals…). It is just that the only place you notice the difference where you felt the pain originally. If your body is sending no pain signals, you can’t notice if they would be quieter.