Inspired by the same question about antibiotics a few days ago. I get that (in the case of NSAIDs) they are reducing inflammation but how? And how do they target my head or back or knee?
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As to the targeting a part of your body question, they don’t. It has the same impact on your whole body (lowering inflammation, lowering pain signals…). It is just that the only place you notice the difference where you felt the pain originally. If your body is sending no pain signals, you can’t notice if they would be quieter.
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