as someone else already said, cells don’t have any type of brain, but what they have are proteins and cell receptors on their membrane and some (immune system cells) have the ability to, basically, read them.
The proteins show the state of any giving cell, so if the cell is dying the proteins will change, and if they’re infected with a virus they’ll present a different type of protein, if the immune system has already fought that virus (meaning at t cell already ate an infected cell) the they are able to recognize it for their protein and kill it before it spreads.
when the body is facing an infection that it has never seen, then we have the neck cells, that are able not only to read the simple changes like the normal t cells, but they’re also able to read almost any change on the cell receptors, to stop it. this no cell deal with cancerous cells as well, but they aren’t foolproof, sometimes they can fail and you get sick
There’s another scenario on which some viruses, stop the cell from represents information on its surface, but there is a type of t cells that are designed to attack the cell when they don’t show anything on their surface
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