How do painkillers know where to target the pain?

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How do painkillers know where to target the pain?

In: Biology

Painkillers don’t target anything. If it’s the painkiller pills u are talking about then they just numb you from feeling any pain rl.

They don’t — they back pain receptors, which are only noticed when ones receiving pain signals no longer do.

They don’t in any manner. They block pain receptors and reduce inflammation in the entire body. The feeling that they target pain is an illusion you experience when you stop getting a pain signal that you have been receiving.

None of these answers are correct. Painkillers do not directly block pain receptors.

First things first. There are many kinds of pain (nociceptive, inflammatory, neuropathy, acute pain, chronic pain, etc.) and there are different ways to treat each one.

When you ask about painkillers, I assume you’re talking about ibuprofen/NSAIDs or acetaminophen/paracetamol. We’ll start with ibuprofen and other NSAIDs.

NSAID stands for non-steroidal anti-inflammatory drug. As the name suggests, NSAIDs treat inflammatory pain. There is an enzyme in your body called cyclooxygenase (COX). Think of an enzyme like a machine that converts one molecule into another. COX is involved in the conversion of arachidonic acid to prostaglandins. These prostaglandins cause inflammation, which in turn, causes pain. The drug goes all around your body, but if prostaglandins aren’t being produced in a certain area, the drug doesn’t work there. That is also why you can still feel other kinds of pain. Like if you pinch yourself, that pain isn’t caused by inflammation, so it still hurts.

Pain killers don’t target anything. They are like killing a fly with a shotgun, you also interfere with other parts of your environment, more Than just the fly