ELI5: DNA gets damaged over time so fresh, new cells – built by faulty instructions – aren’t (as) good. That’s how you get wrinkles and weak bones and such. And one day you’ll get catastrophic organ failure, which we usually mean by “natural death”. Like new heart muscle cells just not being enough to do the job, and such.
Main thing that’s damaging DNA (and thus slowly killing us) is oxygen, but diet, pollution, lifestyle and such is also a factor.
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