How do prenatal paternity tests using SNP markers work?

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Is there any chance a NIPP (non-invasive prenatal paternity test) could yield a false negative result due to some factors (like paternal sample taken was of nails as opposed to the usual cheek swab; mother also has history of miscarriage 2.5 months prior to conception)? NIPP was done at 23 weeks.

I’m just confused as to how they came up with <0.000001% probability when the mismatches (correspond markers) are 300 out of the 1071 tested SNP markers. I’m confused as to how they came up with the results. Does this mean 300 markers didn’t match with the alleged father while the rest out of 1071 matched?

https://imgur.com/a/3Givf7T

In: Biology

2 Answers

Anonymous 0 Comments

Why did you take nails as the dna?!? It’s not cells. It’s doesn’t really have the chromosomes. It’s keratin sheets.

It’s like hair. Hair also doesn’t really have dna. But hair follicles do.
Honestly I think there is a change the dna measured was contamination dna rather than like the dna of the potential father.

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