I’ve just watched a documentary investigating a woman who died due to an unknown cause. It’s mentioned that she was on some medication, but the dose in her blood was lower than what is lethal. How do they check how much of a particular medicine it takes to kill a person without killing a person??
In: Biology
The data comes from experiments in rats and mice. But, there is also data for medicines that people commonly overdose on. There are thousands of people every year that intentionally take overdose on medicine for self harm, and that data can give you an idea of an LD50, based on how much those people were taking and how many of them died.
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