How do topical medications treat things that are not superficial, like headaches or cramps?

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How do topical medications treat things that are not superficial, like headaches or cramps?

In: Biology

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Things like muscle rub that either give your skin a hot or cold feeling do nothing more than distract you from the pain. Muscle pain is not pleasant but the heat from a muscle rub is either not as unpleasant or actually pleasant and your attention is taken away from the muscle ache and on the heat or cold.

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