Two main ways. First, it goes into your pee and gets flushed out.
Second, the liver processes many drugs as unwelcome chemicals and turns them into basic biologic chemicals like amino acids and sugars. This second one is why you can’t have grapefruit juice when on certain drugs. Grapefruit juice destroys an enzyme in your liver involved in deactivating many drugs and you end up risking an overdose. Ordinarily, this isn’t a problem unless you are taking one of these drugs.
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