Years of studying and practical training.
A mental disorder is something that affects your whole life and well-being. There is way more to having something like ADHD, aside from at times feeling hyper.
A psychologist measures the symptoms a person is experiencing against not just the known symptoms of the disorder, but also against how severely those symptoms affect that person’s life.
This is also why so many people struggle or fail to get diagnoses. They may not have the known symptoms as described, or they may have developed such effective coping mechanisms, that their disorder doesn’t affect their life as badly as others’.
As others have said, it’s based on whether it interferes with your day to day life, that does mean that the diagnosis can be a bit subjective and context dependent, but that’s by design. No one can really tell you the “correct” way to live your life, if you like being ultra-hyper and you can find a way to get it to function within your life then great! It’s not a psychologists job to tell you who to be, but to help you if you want to change.
Psychologists and therapists have a reference manual: The DSM V (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition). All named conditions (schizophrenia, anxiety, panic, narcissism, etc.) have a number of “boxes that need to be checked” in order to categorize any one patient as having this or that disorder. So, for example, Narcissism may have nine possible traits; if you have five of these, you can be considered to have Narcissistic Syndrome. This is the way Psychologists try to quantify disorders, rather than just “feel” this is the right diagnosis for a patient.
It’s all definitions. There really isn’t any very good way of measuring any of this. Contrary to many people’s belief, Psychology is NOT a science. They do perform experiments, but as mentioned there is no good way of measuring anything. Psychology and all the “soft” science have what is known as the [Replication Crisis.](https://en.wikipedia.org/wiki/Replication_crisis) Basically they have a hard time reproducing the results of experiments which is at the foundation of the scientific method.
As one person said, they created a book (the DSM) where they can cross reference a list of symptoms against a list of symptoms that they have defined comprise a disorder. If you have match a certain number of symptoms they’ll say you have that disorder.
Your mental experience becomes “clinically significant” when it impairs your ability to lead a happy, functional, independent life. If you cannot eat, sleep, bathe, work, socialize, hobbies, etc. that you would otherwise usually be capable of doing, it is worthy of some sort of clinical intervention.
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