Severe allergic reactions are caused by an antibody called immunoglobulin E overreacting to what it thinks are infections and causing excess histamine to be released which in turn can cause severe reactions possibly leading to anaphylaxis. So anti histamines stop the histamines what they don’t do is combat the thing you are allergic to they just minimise your reaction to it. https://youtu.be/zk_oUk0bwxs
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