How does buprenorphine and naloxone interact with each other in Suboxone? I’ve heard that buprenorphine is more potent than morphine, how does the naloxone prevent this?

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How does buprenorphine and naloxone interact with each other in Suboxone? I’ve heard that buprenorphine is more potent than morphine, how does the naloxone prevent this?

In: Biology

4 Answers

Anonymous 0 Comments

Naloxone is a competitive antagonist. That’s fancy for it is fighting buprenorphine for the same receptor sites, it is just way better at getting them. Naloxone (Narcan) is essentially a much better version of buprenorphine, but it doesn’t get you high.

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