It can happen quite rapidly.
I was a (relatively) healthy alcoholic until this year when #5 in [this list](https://www.reddit.com/r/explainlikeimfive/s/Ed3eZXFzh1) almost killed me in August.
It took me by complete surprise, my feet swole up, I was vomiting constantly and then in withdrawals, shaking and sweating on the toilet pan puking and passing blood. A lot of blood.
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