I went through the searches, there’s a lot of questions about SSRIs, SNRIs, ADHD medications, the mechanics of serotonin and dopamine but I didn’t see a whole ton on quetiapine.
In: Biology
Quetiapine is very technically approved for use in severe depression, but it doesn’t actually treat that depression. Quetiapine’s main use in depression is preventing very severely depressed people from killing themselves. It does this by preventing a person from “thinking” – for lack of a better word, such that they’re so tranquilized that they can’t mentally process the commands necessary to commit suicide.
Quetiapine’s mechanism of action is that it reduces the effects of most major neurotransmitters in the brain, effectively reducing brain activity. This makes its useful in schizophrenia, where the underlying cause of the schizophrenia is too much brain activity, and is also why it has a strong tranquilizing effect in people with depression.
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