I have been on various SSRIs in the past 15 years for anxiety and depression (Prozac, Wellbutrin, Zoloft, Celexa). FYI: I am noticing Celexa is the winner. I have seen in media and criminal defenses that they may cause suicide, further depression, and psychotic episodes. I understand how basic SSRIs work on the brain so how does this happen? What causes the contraindication when these are a drug that should bring mental benefits?
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They can cause suicide risk because people who are being lifted out of severe depression by SSRIs are more likely to attempt suicide because they are still severely depressed but finally have the motivation to give it a shot.
It can get worse because sometimes drugs have the opposite of the intended reaction. This is pretty rare.
I haven’t heard of SSRIs causing psychotic episodes. But I guess it would be possible if it pushed someone into a manic episode which can cause psychosis. Depression can cause it as well but it’s pretty rare.
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