If a Prion can misfold other proteins, why can’t you make an enzyme or another prion that undoes the fold?

Question

I remember hearing that prions like mad cow disease are misfolded proteins that manipulate other proteins they come into contact with. If that’s the case why can’t you use another prion to unfold it and restore it to normal?

In: Biology

Answer 1

Its theoretically possible. We just discovered how prion’s work, chemically designing a protein that fixes it is a long way in the future.

As other posters have stated there are more likely easier ways to cure the disease.