Just swallowed 2 Nyquil and they were unpleasantly large to swallow. Got me wondering.
In: Biology
I used to work in a pharmaceutical compounding lab many years ago. Other things that go into the “excipients” (other stuff besides active ingredients) include “gluidants”, to help the powder flow through a shoot in the capsule filling machine. Surfactants to stop charged power from sticking to metal parts. “Lubricating agents”, “binding” agents to help tablets stick together etc.
I don’t remember all the details, but it was much easier to make a batch of a few capsules by hand, than to figure out a repeatable automated manufacturing process.
Then we would have to test the formulation at every step of the way to prove the right amount of drug was being delivered. Then also later test the capsule or tablet for durability, dissolving, stability at different temperatures. The boss had a phd in all this stuff. There is a lot that goes into it.
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