Not all genes are used in every cell.
Imagine I gave 3 people a general housekeeping book (this is DNA in my metaphore) which contains: recipes, cleaning tips and, sewing instructions etc.
Then I asked one person to bake a cake, one person to do laundry and one person to re-sew a button onto a shirt using the info in the book.
They all have the same total information, but they look at different parts of the book for instructions.
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