: If caloric restriction in mamals works be changing cellular activity into a survive and protect mode, potentially increasing lifespans, why didn’t our prehistoric ancestors with low caloric budgets not live long?

Question

: If caloric restriction in mamals works be changing cellular activity into a survive and protect mode, potentially increasing lifespans, why didn’t our prehistoric ancestors with low caloric budgets not live long?

In: Biology

Answer 1

It’s hard to live long when a scratch can cause you to die a terrible death. Or a caloric restriction goes on for so long that you die. Or a predator eats you. Or a competing male kills you. Or you die in childbirth.