Good things and bad things cause chemical changes in your brain.
For exemple stress release cortisol which is a chemical, and that chemical has real short term but also lasting effects on your brain and body.
There are many other chemicals, their actions are really complex and not completely understood, but it’s not hard to imagine an excess of a chemical can break something in your brain. I’d even say good things can also cause depression, happiness chemicals have bad effects and can cause imbalances and an happy shock is still a shock.
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