If most organ cells, like in the liver, are replaced every three years or so, why isn’t a transplant eventually accepted by the new body?

Question

If most organ cells, like in the liver, are replaced every three years or so, why isn’t a transplant eventually accepted by the new body?

In: 350

Answer 1

what exactly are you replacing?

if the original liver had to be removed for a transplant, the new organ is not using the former’s hepatocytes(liver’s precursor cells) because they are not present anymore.

whatever replacement these cells do is gonna be based on the donor’s cells.