I’m not an expert but speaking from experience, sometimes people have various conditions that can mess with the body’s internal signals. They might not feel full even if they have eaten enough, they might not feel like they have to use the washroom until they’re nearly bursting, stuff like that. There’s also the option to ignore those signals and keep eating for reasons other than sustenance. I, for example, am an emotional eater. If I’m full but still feel bad, I may choose to keep eating to comfort myself. I certainly feel sick afterwards, but my emotions are satisfied for the moment.
There’s also the issue that the more weight you gain and the more you don’t listen to your body’s signals, the more screwed up they become, making it easier to over eat.
Finally, there are other factors that can affect your weight such as medications or other conditions that affect things like insulin resistance and weight retention. I started gaining weight when I was put on antidepressants when I was 7. Those, in combination with my emotional eating, led to weight gain.
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