if protein is broken down into peptides in the stomach/digestive tract, why would consuming something like “active collagen” do anything?

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I’m basically wondering like what effect is it having if it’s broken down into peptides in the stomach before absorption in the system, or is it one of those things that’s somehow absorbed by the bloodstream before digestion (like some medications)

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33 Answers

Anonymous 0 Comments

In general, the efficacy of most supplements is debatable. If you actually read the documentation on most of them, you’ll notice that they’re rather vague on what they actually DO. In many cases, they have absolutely no scientific evidence to suggest they actually do what they claim, so they leave their claims to vague phrases like “digestive health” or “joint health”. There are also concerns about the safety of them if they did work (e.g., a supplement that claims to increase breast size and actually does? What the hell is it doing to your body to do that?)

The only supplements with any real evidence are the micronutrient ones (i.e., “vitamins”) and only if you have a specific deficiency (e.g., calcium supplements for someone who’s severely lactose intolerant).

Tldr, most supplements are at best useless or at worse harmful.

Anonymous 0 Comments

There is in fact a lot of animal and clinical evidence that supports collagen hydrolysate (assuming this is what you meant by active collagen) supplementation for skin aging: [Recent progress in preventive effect of collagen peptides on photoaging skin and action mechanism](https://www.sciencedirect.com/science/article/pii/S2213453021000975)

The human digestion is a slow process catalyzed by digestive enzymes. Short collagen chains can be absorbed quickly into the blood stream while longer collagen chains are too big to be absorbed and are mixed with the digestive enzymes and broken down into peptides. Collagen hydrolysate are made by using heat or acid to controllably partially digest long collagen fibrils into shorter chains for fast absorption. Aging skin produces less collagen. The wrinkling we see on old people’s faces are caused by this change in the material composition of their skin. The short collagen chains travel through the blood stream to the skin and are incorporated into cell-produced collagen fibers, making up for the loss of collagen production caused by aging.

Anonymous 0 Comments

There is in fact a lot of animal and clinical evidence that supports collagen hydrolysate (assuming this is what you meant by active collagen) supplementation for skin aging: [Recent progress in preventive effect of collagen peptides on photoaging skin and action mechanism](https://www.sciencedirect.com/science/article/pii/S2213453021000975)

The human digestion is a slow process catalyzed by digestive enzymes. Short collagen chains can be absorbed quickly into the blood stream while longer collagen chains are too big to be absorbed and are mixed with the digestive enzymes and broken down into peptides. Collagen hydrolysate are made by using heat or acid to controllably partially digest long collagen fibrils into shorter chains for fast absorption. Aging skin produces less collagen. The wrinkling we see on old people’s faces are caused by this change in the material composition of their skin. The short collagen chains travel through the blood stream to the skin and are incorporated into cell-produced collagen fibers, making up for the loss of collagen production caused by aging.

Anonymous 0 Comments

There is in fact a lot of animal and clinical evidence that supports collagen hydrolysate (assuming this is what you meant by active collagen) supplementation for skin aging: [Recent progress in preventive effect of collagen peptides on photoaging skin and action mechanism](https://www.sciencedirect.com/science/article/pii/S2213453021000975)

The human digestion is a slow process catalyzed by digestive enzymes. Short collagen chains can be absorbed quickly into the blood stream while longer collagen chains are too big to be absorbed and are mixed with the digestive enzymes and broken down into peptides. Collagen hydrolysate are made by using heat or acid to controllably partially digest long collagen fibrils into shorter chains for fast absorption. Aging skin produces less collagen. The wrinkling we see on old people’s faces are caused by this change in the material composition of their skin. The short collagen chains travel through the blood stream to the skin and are incorporated into cell-produced collagen fibers, making up for the loss of collagen production caused by aging.

Anonymous 0 Comments

I have a genetic issue that influences collagen synthesis in the body, and every now and then some other people with my condition try to “medicate” themselves by eating collagen. No way that will ever do anything as the stuff does not go into the body as is. It’s broken up and new collagen is built from available raw materials, using the messed up process.

Anonymous 0 Comments

I have a genetic issue that influences collagen synthesis in the body, and every now and then some other people with my condition try to “medicate” themselves by eating collagen. No way that will ever do anything as the stuff does not go into the body as is. It’s broken up and new collagen is built from available raw materials, using the messed up process.

Anonymous 0 Comments

I have a genetic issue that influences collagen synthesis in the body, and every now and then some other people with my condition try to “medicate” themselves by eating collagen. No way that will ever do anything as the stuff does not go into the body as is. It’s broken up and new collagen is built from available raw materials, using the messed up process.

Anonymous 0 Comments

For complex proteins, taking oral supplements of something like collagen probably doesn’t do much. There is little scientific evidence to show that it helps, and most of those studies are funded by the companies trying to sell you the supplements.

Best thing you can do for your skin long-term is avoid sun damage by wearing SPF.

Anonymous 0 Comments

For complex proteins, taking oral supplements of something like collagen probably doesn’t do much. There is little scientific evidence to show that it helps, and most of those studies are funded by the companies trying to sell you the supplements.

Best thing you can do for your skin long-term is avoid sun damage by wearing SPF.

Anonymous 0 Comments

For complex proteins, taking oral supplements of something like collagen probably doesn’t do much. There is little scientific evidence to show that it helps, and most of those studies are funded by the companies trying to sell you the supplements.

Best thing you can do for your skin long-term is avoid sun damage by wearing SPF.