We know the brain is always trying to find a stasis which is why we build tolerance to caffeine, alcohol, etc. If that is the case, how would it be possible for any external medication to come in and fix your brain chemistry without creating a tolerance. Are people with imbalance disorders doomed to always ride a rollercoaster of tolerance building and detoxing. For example, wouldn’t any attempt to increase dopamine levels in people with ADHD just cause the brain to eventually bring the new levels back down to the disordered levels?
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It’s all related to therapeutic levels of the drug.
The concept is to day-after-day reach the levels that provide benefit while not reaching toxic levels (high) or ineffective levels (low).
Not easy or straightforward…
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