The biggest hurdle for any medicine is the test of time. Over the years paracetamol has seen countless tests so we exactly know what kind of effects can come out of it so as to treat it promptly.
There’s precautions to be taken and a dosage identified completely known to us, while the exact cogs ticking behind the scenes may not be fully be known we have a good data of how it affects everyone and hence treated as a over the shelf drug
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