If vesicles can fuse to membranes fairly easily, what’s there to stop a whole bunch of cells fusing together?

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If vesicles can fuse to membranes fairly easily, what’s there to stop a whole bunch of cells fusing together?

In: Biology

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Anonymous 0 Comments

Cell membranes are different from vesicles. They contain anti-fusing lipids like Lysolipids. Also, they have phospholipids that are negatively charged and repel each other.

Basically, it is energetically unfavourable for cell membrane fusion to occur and will not happen spontaneously. You need deliberate energy expenditure to merge cells, such as monocytes merging into macrophages.

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