Sorry if this is convoluted, tried to express this in the clearest way I know how
In: Biology
It…normally doesn’t?
If you viewed the skin microscopically you’d see that it is made up of different layers. On the surface, are mostly “dead” cells, (a layer of a protein called keratin). Beneath this, are multiple layers of maturing and matured cells. Underneath all of those is the final layer of cells, called the “basal” layer.
The basal layer are the only cells that can divide and therefore these cells still need to be alive in order for the skin to regenerate. If the skin is split above this layer, as long as the basal cells (which can be quite fragile) are left intact, the basal cells will grow a new layer of skin.
If you have wound in which the full thickness of the skin has been lost, only the basal cells at the edge of the wound can duplicate. It will take more time for these edge cells to grow across the wound to cover it.
There is no innate mechanism by which the superficial layers of skin can reattach themselves to the layers beneath them.
If the wound is immediately below the basal layer, it usually means that the basal cells have been separated from their blood supply. In most cases this means that the basal cells will eventually die.
If the wound is deep enough that the skin comes away but still has a viable blood supply, it it possible that the skin could be repositioned and recover.
Cells are living things, and they secrete a bunch of chemical signals to direct where the healing takes place, the raw wound is secreting these signals to tell where the wound is and that this is the place where they should start to for blood clots and fibrin and all that to start the regeneration process.
Hope this explanation was adequate
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