Technically this pretty much has to happen at some point, because we have two major theories at the moment describing how the universe works–quantum theory at very small scales, and relativity theory at large scales. The problem is, those theories contradict each other in some details, so they both can’t be 100% correct. At some point someone will figure out a theory that works at both large and small scales consistently, the so-called “Grand Unified Theory”, and something in that is going to disprove something in one of those big theories, it pretty much has to.
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