This subject has naturally been researched. Here two of them. The second is rather interesting.
[Cannabis Addiction and the Brain: a Review](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223748/)
[Lifetime marijuana use and epigenetic age acceleration: A 17-year
prospective examination](https://www.dalgarnoinstitute.org.au/images/resources/pdf/cannabis-conundrum/Lifetime_marijuana_use_and_epigenetic_age_acceleration_-_A_17-year_prospective_examination22.pdf)
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