I hear and see a lot of mention of weight gain as a side effect of some medications. I believe it happens but I’ve never understood how it works. For example, could an athlete who eats perfectly still be struck by weight gain as a side effect? What’s the biological mechanism that would make weight gain happen in a person with a healthy balanced diet?
I’ve taken a medication for years that a doctor just told me they’d rather never raise the dose on because it can cause metabolic syndrome. My A1C, cholesterol, and virtually the rest of my labs were in the healthy range, but I have noticed some weight on me that seemed oddly persistent. My diet ranges from average to healthy nowadays and I’m moderately active. Yet I can think back to a time before the medication when I was eating horribly, never exercised, smoked and drank nonstop, and my labs were looking nasty – yet my extremely consistent max weight was a solid 20lbs under what it is today which a noticeably better lifestyle all around. I’m by no means the athlete in the perfect diet example, I’m more fascinated by how something like that is even possible. Definitely interesting.
In: Biology
Broadly three main ways
1.) Cauase the body to remain more water and salts
2.) increase appetite or decrease energy and thus activity levels.
3.) decrease metabolism. These are mostly neuromeds that reduce the energy your brain uses but there are others.
If you were on a pro athlete regime and tracking everything you could account for two and three by altering your diet. Might feel awful and or constantly hungry doing so though.
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