It is impossible for necrotic tissue to be reversed, it’s biologically inert… It is absolutely an infection problem since it provides a space where bacteria can reproduce, which the immune system is unable to attack. It also, in case of wounds, slows the natural healing process, since it’s like a pile of debris that needs to be cleared before be tissue can be “laid down”…
The main progress that’s being made is around better/safer/less painful/less destructive methods of debridement (clearing the necrotic tissue) so the bodies natural healing can take over. Using larval dressings is pretty cool, although kinda gross…
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