– The drug “Skyrizi” is advertised in the US as a treatment for 3 seemingly different afflictions – 1) plaque psoriasis, Crohn’s disease, and psoriatic arthritis. How is that possible?

Question

My post is not meant as an ad for that drug.

In the US, we are bombarded with TV ads for drugs, and this drug has some catchy songs they play while advertising stuff. But I noticed that the same drug was advertised to 3 different audiences for 3 different afflictions.

Are these 3 afflictions somehow medically related? How does this one drug solve issues for 3 (to the layman, seemingly) different medical diagnoses?

In: 4

Answer 1

All of those afflictions are caused by an overactive immune system, and Skyrizi works by dampening that immune response. By turning down that reponse, the symptoms for those conditions can improve. That’s why the side effects are so severe. If you turn off your immune system, you’re much more likely to get sick from other diseases.