Of course.
The sensation is driven by nerves, right?
Anything that irritates the nerve, can trigger sensations that aren’t being driven by tissue damage.
For instance, spicy food only feels like your mouth is on fire. Same sensation as burning, but no tissue damage.
And if nerves are “turned off”, even when there is extensive tissue damage, there will be no sensation of pain.
This is how an epidural works during childbirth.
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