What does a “fast/slow metabolism” really mean?

Question

I mean, I get that having a fast metabolism means that you get fat harder and vice versa, but what does it exactly mean? And what are the upsides and downsides of each?

In: Biology

Answer 1

This is an interesting topic.. A “fast metabolism” is often associated with the physiological phenomenon of “mitochondrial uncoupling”. This is a process where the mitochondria produce more energy than they need or can effectively use, producing more waste heat and an effusion of metabolic byproducts, but generally fewer of the metabolically harmful, degeneration-inducing ROS(reactive oxygen species). Think of it like a fire. A hot fire burns clean. It produces less soot. This process of mitochondrial uncoupling is, in some circumstances, associated with increased lifespan.