My assumption is that over time the organ regenerates new cells with the host’s DNA. Or do the two stay distinct for life, or do they merge into a mix of the two? If they stay separate, is there a definite boundary, and does the host’s future offspring bear the DNA of three bloodlines instead of two?
In: Biology
It is possible that there will be some mixing of cells, given the possibility of cells to enter the cell flow and exit in a different district (fibroblasts, macrophages), but they will generally stay separated. There is also the possibility that DNA or RNA shed from the host or donor cells are uptaken by the other type of cells, but I don’t know if this phenomenon has been studied.
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